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Sickle Cell Disease (SCD) is the most frequent genetic disease worldwide.

SCD is present in four continents: Sub-Saharan Africa and in the Maghrib, in Asia (Middle-East, Arabic peninsula, India), in the Americas, on the North (USA), centre (Guatemala, Caribbean islands), and on the South (Brazil, Surinam, Guiana), in Southern Europe (Southern Italy and Sicily, Greece, Turkey).

It is estimated that 500, 000 are born every year with this severe and invalidating condition and that 50% of them will die before the age of 5 years.